Antiphospholipid Syndrome Presented with Pulmonary Embolism and Deep Venous Thrombosis in Child.
- Author:
Ran LEE
1
;
Il Soo HA
;
Hae Il CHEONG
;
Yong CHOI
Author Information
1. Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Antiphospholipid syndrome;
Pulmonary embolism;
Deep Vein thrombosis
- MeSH:
Adolescent;
Antibodies, Antinuclear;
Antiphospholipid Syndrome*;
Child*;
Diagnosis;
Dyspnea;
Female;
Femoral Vein;
Humans;
Lung;
Lupus Coagulation Inhibitor;
Prednisolone;
Pulmonary Embolism*;
Thrombocytopenia;
Thrombosis;
Ultrasonography;
Venous Thrombosis*
- From:Journal of the Korean Pediatric Society
1996;39(5):722-726
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Antiphospholipid syndrome is a thrombotic disorder and the serologic marker of the syndrome is antiphospholipid antibody(lupus anticoagulant, anticardiolpin antibody, or both). In a 13-year-old girl who presented with dyspnea, pulmonary embolism and femoral vein thrombosis were demonstrated by lung scan and abdominal ultrasonography. She had 3 out of 11 criteria for the diagnosis of SLE, such as thrombocytopenia, positive antinuclear antibody, low C3 and high anti-ds-DNA Ab, but did not meet whole criteria. And lupus anticoagulant was positive. She was treated with anticoagulants(heparin and wafarin) and prednisolone. Antiphospholipid antibody(lupus anticoagulant and anticardiolipin antibody) should be checked in children with thrombosis occurring without a known predisposing cause.
