Application and prospect of alkyl polyglycosides absorption enhancers in drug delivery system
10.16438/j.0513-4870.2020-1882
- VernacularTitle:烷基糖苷类吸收促进剂在药物递送系统中的应用与展望
- Author:
Xian-fu LI
;
Zhi-wei ZHANG
;
Xiao-xuan HONG
;
Xiao-lu HAN
;
Meng LI
;
Zeng-ming WANG
;
Ai-ping ZHENG
- Publication Type:Research Article
- Keywords:
alkyl polyglycoside;
penetration enhancer;
biofilm;
safety;
rug delivery system
- From:
Acta Pharmaceutica Sinica
2021;56(6):1591-1598
- CountryChina
- Language:Chinese
-
Abstract:
The efficient and safe delivery of drugs to the therapeutic site through the biofilm has traditionally been a difficult and hot topic in the field of drug delivery. In recent years, alkyl polyglycoside (APG) have become ideal penetration enhancers for drug delivery systems because of their high permeability, good safety and biodegradability, which has attracted wide attention of domestic and foreign researchers. In this paper, the physical and chemical properties, characteristics, action mechanism and application of APG in drug delivery system are reviewed, and its application prospect in drug delivery system is prospected.
