Analysis on the suspected adverse events following immunization surveillance reports of pneumonia vaccine in Shanghai， 2010‒2020
10.19428/j.cnki.sjpm.2021.21138
- VernacularTitle:2010—2020年上海市肺炎疫苗的疑似预防接种异常反应报告的分析
- Author:
Shou-fei YANG
1
;
Zhuo-ying HUANG
1
;
Jia REN
1
;
Jie-chen LIU
1
Author Information
1. Department of Immunization， Shanghai Municipal Center for Disease Control and Prevention， Shanghai 200336，China
- Publication Type:Research Article
- Keywords:
pneumonia vaccine;
surveillance;
safety evaluation;
adverse events following immunization
- From:
Shanghai Journal of Preventive Medicine
2021;33(6):548-552
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the collected data of adverse events （AEFI） of pneumonia vaccine in Shanghai from 2010 to 2020，， so as to provide the appropriate immunization strategy and popularization of science for pneumonia vaccine . Methods:the data of suspected adverse events were collected from National AEFI Surveillance System during 2010 to 2020， and the vaccination information of pneumonia vaccine was obtained from Shanghai Vaccination Information System. Descriptive epidemiological method was used to analysis. Results:The total 18 446 AEFI cases were reported in Shanghai from 2010 to 2020， and the incidence rate was 425.0/100 000 doses. The general reactions were reported as 18 003 cases （97.6%）， with 393 cases of abnormal reactions （2.0%）， 57 cases of coincidences （0.3%）， 2 cases of psychogenic reactions （<0.1%） and no vaccine quality accident or vaccination accident was reported. There was no significant difference in the incidence rate between male and female； The incidence rate of AEFI decreased with the age of the old. The incidence rate of 23 valent pneumococcal polysaccharide vaccine （PPV23） AEFI was 476.5/100 000 doses， which was significantly lower than that of other kinds of pneumonia vaccine. The first dose was also significantly higher than that of non-first dose. Conclusion:The various types of pneumonia vaccines being used in Shanghai have high safety.
