Association between sleep with C reactive protein and insulin metabolism in adolescents
10.16835/j.cnki.1000-9817.2021.06.005
- VernacularTitle:青少年睡眠与C-反应蛋白及胰岛素代谢的相关性
- Author:
TANG Yuqing, LI Liwen, LYU Jiajun, CHEN Yiting, WANG Xiaobin, LI Shenghui
1
Author Information
1. School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai(200025), China
- Publication Type:期刊文章
- Keywords:
Sleep;
C reactive protein;
Insulin;
Regression analysis;
Adolescent
- From:
Chinese Journal of School Health
2021;42(6):819-822
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship of sleep with C reactive protein (CRP) abnormality and hyperinsulinemia in adolescents, and to provide reference for early prevention of metabolic disorders.
Methods:Based on the Chinese Metabolic Syndrome Cohort Study in Anhui Province, a total of 653 adolescents aged 12 to 19 were selected to examine the relationship between wakeup time, bedtime, sleep disordered breathing (SDB) and CRP abnormality as well as hyperinsulinemia.
Results:Later wakeup time (OR=1.68, 95%CI=1.03-2.75) was positively correlated with a higher risk of fasting hyperinsulinemia. Late bedtime (OR=1.96, 95%CI=1.29-2.99) was associated with 2 h postprandial hyperinsulinemia. Among those with high CRP concentration, late wakeup time and late bedtime were positely associated with hyperinsulinemia than those with normal CRP concentration; and the correlation between SDB and hyperinsulinemia was observed.
Conclusion:Later wakeup and late bedtime may be risk factors for hyperinsulinemia in adolescents. High concentrations of CRP may further increase the risk of hyperinsulinemia, a condition associated with sleep problems.Teenagers should get up and go to bed as early as possible.
