The impact of masticatory dysfunction caused by occlusal disharmony on cognitive function
10.12016/j.issn.2096-1456.2021.09.012
- Author:
OU Yanzhen
1
;
LI Baosheng
1
;
CAI Qing
1
;
JIANG Jiayang
1
;
Jiayang Zhuohua
1
;
MENG Weiyan
1
Author Information
1. Oral Implantology Department, School and Hospital of Stomatology, Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Jilin University
- Publication Type:Review
- Keywords:
occlusal disharmony;
masticatory dysfunction;
cognitive function;
Alzheimer’s disease;
hippocampus;
hypothalamic-pituitary-adrenal axis;
cerebral blood flow;
chronic stress;
nutrition
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2021;29(9):644-648
- CountryChina
- Language:Chinese
-
Abstract:
As the world’s population ages, age-related cognitive decline and dementia are becoming important challenges for geriatric care. Despite the ongoing search for solutions to address cognitive decline, effective interventions have not yet been established. There is increasing evidence from clinical, epidemiological, and animal studies that masticatory dysfunction due to occlusal disharmony is a risk factor for cognitive decline and an increased incidence of dementia. The mechanisms may involve altered nutritional intake, decreased cerebral blood flow, chronic stress, and hippocampal morphological function. These findings suggest that maintaining and adequately restoring the entire masticatory system has a positive impact for the prevention of cognitive decline.
- Full text:咬合不协调所致咀嚼功能障碍对认知功能的影响.pdf