Effectiveness of uniportal video-assisted thoracoscopic sublobar resection and lobectomy for lung metastases from colorectal cancer
- VernacularTitle:单孔电视胸腔镜亚肺叶与肺叶切除治疗结直肠癌肺转移瘤的效果分析
- Author:
Wei WU
1
;
Ni ZHANG
2
;
Changyu LIU
2
Author Information
1. Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, P.R.China
2. Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, P.R.China
- Publication Type:Journal Article
- Keywords:
Colorectal cancer;
lung metastases;
sublobar resection;
lobectomy;
uniportal video-assisted thoracoscopic surgery
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2021;28(05):540-544
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effectiveness of sublobar resection and lobectomy via uniportal video-assisted thoracoscopic surgery (U-VATS) for lung metastases from colorectal cancer. Methods Retrospective research was conducted on 42 colorectal cancer patients with lung metastases who underwent U-VATS sublobar resection and lobectomy at the Tongji Hospital, Huazhong University of Science and Technology between April 2016 and May 2019, including 24 males and 18 females with an average age of 58.0±9.9 years. Among them 17 patients received U-VATS sublobar resection and 25 patients received lobectomy. The operation time, intraoperative blood loss, postoperative pulmonary infection, drainage tube indwelling time, drainage volume on the first day after surgery, postoperative hospital stay were analyzed between the two groups, and the relationship between the prognosis and clinical characteristics of the two groups was compared. Results Sublobar resection patients had less lung metastases (P=0.043) and shorter operation time (P=0.023) compared with the lobectomy patients. There was no significant difference between the lobectomy and sublobar resection groups in intraoperative blood loss (P=0.169), rate of postoperative infection (P=0.982), postoperative drainage duration (P=0.265), drainage volume on the first day after surgery (P=0.402) and postoperative hospital stay (P=0.612). The progression-free survival of the two groups was 25.19 months and 23.63 months (P=0.721), and their overall survival was 29.09 months and 30.64 months (P=0.554). Conclusion Considering guantity and locations of lung metastases, U-VATS sublobar resection can achieve a similar prognosis to lobectomy for lung metastases from colorectal cancer. Further efficacy of this surgical strategy remains to be proved by longer follow-up.
