Impact of particle size and pH on protein corona formation of solid lipid nanoparticles: A proof-of-concept study.
- Author:
Wenhao WANG
1
;
Zhengwei HUANG
1
;
Yanbei LI
1
;
Wenhua WANG
1
;
Jiayu SHI
1
;
Fangqin FU
2
;
Ying HUANG
2
;
Xin PAN
1
;
Chuanbin WU
1
Author Information
- Publication Type:Journal Article
- Keywords: BSA corona-Caused aggregation; Cell uptake; Conformational structure; Medium pH; Nanoparticle-protein interaction; Protein corona; Size effect; Solid lipid nanoparticles
- From: Acta Pharmaceutica Sinica B 2021;11(4):1030-1046
- CountryChina
- Language:English
- Abstract: When nanoparticles were introduced into the biological media, the protein corona would be formed, which endowed the nanoparticles with new bio-identities. Thus, controlling protein corona formation is critical to