Effect of physicochemical properties on
10.1016/j.apsb.2021.03.007
- Author:
Yongchao WANG
1
;
Jinjin WANG
2
;
Dandan ZHU
1
;
Yufei WANG
2
;
Guangchao QING
2
;
Yuxuan ZHANG
2
;
Xiaoxuan LIU
1
;
Xing-Jie LIANG
2
Author Information
1. State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, Center of Advanced Pharmaceutics and Biomaterials, China Pharmaceutical University, Nanjing 210009, China.
2. Laboratory of Controllable Nanopharmaceuticals, Chinese Academy of Sciences (CAS) Center for Excellence in Nanoscience and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China.
- Publication Type:Review
- Keywords:
Cancer treatment;
Cellular uptake;
Immune responses;
Intracellular transfer;
In vivo fate;
Lymph nodes drainage;
Nanoparticle-based cancer immunotherapies;
Physicochemical properties
- From:
Acta Pharmaceutica Sinica B
2021;11(4):886-902
- CountryChina
- Language:English
-
Abstract:
Current advances of immunotherapy have greatly changed the way of cancer treatment. At the same time, a great number of nanoparticle-based cancer immunotherapies (NBCIs) have also been explored to elicit potent immune responses against tumors. However, few NBCIs are nearly in the clinical trial which is mainly ascribed to a lack understanding of
