Selectively enhancing radiosensitivity of cancer cells

Author: Yang GAO ¹ ; Jie GAO ¹ ; Ganen MU ¹ ; Yumin ZHANG ¹ ; Fan HUANG ¹ ; Wenxue ZHANG ² ; Chunhua REN ¹ ; Cuihong YANG ¹ ; Jianfeng LIU ¹
Author Information

1. Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.
2. Radiation Oncology Department, Tianjin Medical University General Hospital, Tianjin 300052, China.
Publication Type:Journal Article
Keywords: Alkaline phosphatase (ALP); Cancer radiotherapy; Histone deacetylases inhibitor (HDACI); In situ enzyme-instructed self-assembly (EISA); Nanofiber; Peptide; Pre-assembly; Radiosensitizer
From: Acta Pharmaceutica Sinica B 2020;10(12):2374-2383
CountryChina
Language:English
Abstract: The radiotherapy modulators used in clinic have disadvantages of high toxicity and low selectivity. For the first time, we used the