Sirt1 regulates testosterone biosynthesis in Leydig cells via modulating autophagy.
10.1007/s13238-020-00771-1
- Author:
Muhammad Babar KHAWAR
1
;
Chao LIU
1
;
Fengyi GAO
2
;
Hui GAO
1
;
Wenwen LIU
1
;
Tingting HAN
3
;
Lina WANG
1
;
Guoping LI
4
;
Hui JIANG
5
;
Wei LI
6
Author Information
1. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
2. School of Biotechnology and Food, Shangqiu Normal University, Shangqiu, 476000, China.
3. The MOH key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, China.
4. The MOH key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, China. guoping_li@yahoo.com.
5. Department of Urology, Peking University Third Hospital, Beijing, 100191, China. jianghui55@163.com.
6. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China. leways@ioz.ac.cn.
- Publication Type:Research Support, Non-U.S. Gov't
- MeSH:
Animals;
Autophagy/genetics*;
Cholesterol/metabolism*;
Gene Expression Regulation;
Integrases/metabolism*;
Leydig Cells/metabolism*;
Male;
Mice, Knockout;
Multienzyme Complexes/metabolism*;
Phosphoproteins/metabolism*;
Primary Cell Culture;
Progesterone Reductase/metabolism*;
RNA Splicing Factors/metabolism*;
Scavenger Receptors, Class B/metabolism*;
Sequestosome-1 Protein/metabolism*;
Signal Transduction;
Sirtuin 1/genetics*;
Sodium-Hydrogen Exchangers/metabolism*;
Steroid 17-alpha-Hydroxylase/metabolism*;
Steroid Isomerases/metabolism*;
Testosterone/genetics*
- From:
Protein & Cell
2021;12(1):67-75
- CountryChina
- Language:English
