Dynamic cell transition and immune response landscapes of axolotl limb regeneration revealed by single-cell analysis.

Hanbo LI; Xiaoyu Wei; Li Zhou; Weiqi Zhang; Chen Wang; Yang Guo; Denghui LI; Jianyang Chen; Tianbin Liu; Yingying Zhang; Shuai MA; Congyan Wang; Fujian Tan; Jiangshan XU; Yang Liu; Yue Yuan; Liang Chen; Qiaoran Wang; Jing QU; Yue Shen; Shanshan Liu; Guangyi Fan; Longqi Liu; Xin Liu; Yong Hou; Guang-hui Liu; Ying GU; Xun XU

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Dynamic cell transition and immune response landscapes of axolotl limb regeneration revealed by single-cell analysis.

Author: Hanbo LI ¹ ; Xiaoyu WEI ¹ ; Li ZHOU ¹ ; Weiqi ZHANG ² ; Chen WANG ¹ ; Yang GUO ³ ; Denghui LI ³ ; Jianyang CHEN ³ ; Tianbin LIU ¹ ; Yingying ZHANG ³ ; Shuai MA ⁴ ; Congyan WANG ³ ; Fujian TAN ³ ; Jiangshan XU ¹ ; Yang LIU ¹ ; Yue YUAN ¹ ; Liang CHEN ⁵ ; Qiaoran WANG ² ; Jing QU ⁴ ; Yue SHEN ¹ ; Shanshan LIU ¹ ; Guangyi FAN ¹ ; Longqi LIU ¹ ; Xin LIU ¹ ; Yong HOU ¹ ; Guang-Hui LIU ⁶ ; Ying GU ⁷ ; Xun XU ⁸
Author Information

1. BGI-Shenzhen, Shenzhen, 518083, China.
2. CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, China National Center for Bioinformation, Chinese Academy of Sciences, Beijing, 100101, China.
3. BGI-Qingdao, Qingdao, 266555, China.
4. University of Chinese Academy of Sciences, Beijing, 100049, China.
5. Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 40072, China.
6. University of Chinese Academy of Sciences, Beijing, 100049, China. ghliu@ioz.ac.cn.
7. BGI-Shenzhen, Shenzhen, 518083, China. guying@genomics.cn.
8. BGI-Shenzhen, Shenzhen, 518083, China. xuxun@genomics.cn.
Publication Type:Research Support, Non-U.S. Gov't
MeSH: Ambystoma mexicanum/immunology*; Amputation; Animals; Biomarkers/metabolism*; Blastomeres/immunology*; Cell Lineage/immunology*; Connective Tissue Cells/immunology*; Epithelial Cells/immunology*; Forelimb; Gene Expression; High-Throughput Nucleotide Sequencing; Humans; Immunity; Peroxiredoxins/immunology*; Regeneration/immunology*; Regenerative Medicine/methods*; Single-Cell Analysis/methods*
From: Protein & Cell 2021;12(1):57-66
CountryChina
Language:English