O-GlcNAc transferase regulates centriole behavior and intraflagellar transport to promote ciliogenesis.

Author: Fan YU ¹ ; Te LI ¹ ; Yanchao SUI ² ; Qingxia CHEN ³ ; Song YANG ¹ ; Jia YANG ¹ ; Renjie HONG ¹ ; Dengwen LI ¹ ; Xiumin YAN ³ ; Wei ZHAO ² ; Xueliang ZHU ³ ; Jun ZHOU ⁴
Author Information

1. Department of Genetics and Cell Biology, College of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Protein Science, Key Laboratory of Bioactive Materials of the Ministry of Education, Nankai University, Tianjin, 300071, China.
2. College of Pharmacy, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, 300071, China.
3. State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, 200031, China.
4. Department of Genetics and Cell Biology, College of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Protein Science, Key Laboratory of Bioactive Materials of the Ministry of Education, Nankai University, Tianjin, 300071, China. junzhou@nankai.edu.cn.
Publication Type:Research Support, Non-U.S. Gov't
MeSH: Animals; Biological Transport, Active/physiology*; Centrioles/metabolism*; Cilia/metabolism*; Mice; Mice, Mutant Strains; N-Acetylglucosaminyltransferases/metabolism*
From: Protein & Cell 2020;11(11):852-857
CountryChina
Language:English