Clinical efficacy of restrictive fluid management in patients with severe traumatic brain injury.
10.12122/j.issn.1673-4254.2021.01.16
- Author:
Shibing ZHAO
1
;
Decai XU
2
;
Rui LI
1
;
Qi ZOU
1
;
Zhenzhen CHEN
1
;
Huaxue WANG
1
;
Xiandi HE
1
Author Information
1. Department of Critical Medicine, First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, China.
2. Department of Neurosurgery, First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, China.
- Publication Type:Journal Article
- Keywords:
middle cerebral artery pulsatility index;
neuron-specific enolase;
optic nerve sheath diameter;
restrictive fluid management strategy;
severe traumatic brain injury
- MeSH:
Brain Injuries, Traumatic/therapy*;
Fluid Therapy;
Humans;
Prognosis;
Respiration, Artificial;
Treatment Outcome
- From:
Journal of Southern Medical University
2021;41(1):111-115
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the effects of restrictive fluid management in patients with severe traumatic brain injury (sTBI).
METHODS:Between January, 2019 and June, 2020, we randomly assigned 51 postoperative patients (stay in the ICU of no less than 7 days) with sTBI into treatment group (
RESULTS:The cumulative fluid balance of the two groups were positive on day 1 and negative on days 3 and 7 after ICU admission; at the same time points, the patients in the treatment group had significantly greater negative fluid balance than those in the control group (
CONCLUSIONS:Restrictive fluid management can reduce cerebral edema and improve the prognosis but does not affect the 28-day mortality of patients with sTBI.
