Clinical characteristics and treatment outcomes of first peritonitis in patients receiving long-term peritoneal dialysis: a multicenter study.
10.12122/j.issn.1673-4254.2020.12.07
- Author:
Jing ZHAO
1
;
Liming YANG
2
;
Xueyan ZHU
3
;
Xiaoxuan ZHANG
4
;
Xinyang LI
1
;
Shichen LIU
1
;
Xiaohua ZHUANG
1
;
Wenhua ZHOU
1
;
Ping LUO
1
;
Wenpeng CUI
1
Author Information
1. Department of Nephrology, Second Hospital of Jilin University, Changchun 130041, China.
2. Department of Nephrology, Second Division of First Hospital of Jilin University, Changchun 130031, China.
3. Department of Nephrology, Jilin Central Hospital, Jilin 132011, China.
4. Department of Nephrology, Jilin FAW General Hospital, Changchun 130011, China.
- Publication Type:Multicenter Study
- Keywords:
long-term dialysis;
peritoneal dialysis;
peritonitis
- MeSH:
Humans;
Kidney Failure, Chronic/therapy*;
Peritoneal Dialysis/adverse effects*;
Peritonitis/etiology*;
Retrospective Studies;
Treatment Outcome
- From:
Journal of Southern Medical University
2020;40(12):1740-1746
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the clinical characteristics and treatment outcomes of the first episode of peritoneal dialysis-associated peritonitis (PDAP) in patients receiving long-term peritoneal dialysis.
METHODS:The clinical data of patients with the first episode of PDAP in 4 general hospitals in Jilin Province from 2013 to 2019 were collected retrospectively. According to the duration of dialysis, the patients were divided into long-term (≥36 months) and short-term (< 36 months) dialysis groups for comparison of the clinical data, treatment outcomes and long-term prognostic events.
RESULTS:A total of 625 patients with PDAP were enrolled, including 93 on long-term and 532 on short-term dialysis. Compared with those on short-term dialysis, the patients on long-term dialysis had significantly higher hemoglobin levels and lower glomerular filtration rates when the first episode of PDAP occurred (
CONCLUSIONS:Compared with those on short-term dialysis, patients on long-term dialysis are prone to gram-negative bacterial infection when the first episode of PDAP occurs with worse treatment outcomes but similar long-term outcomes. Long-term dialysis is an independent risk factor of extubation and treatment failure for the first episode of PDAP, and fungal and mixed bacterial infections are independent risk factors for treatment failure of the first PDAP in patients with long-term dialysis.
