Hydroxychavicol, a polyphenol from

Author: Aiysvariyah RAJEDADRAM ¹ ; Kar Yong PIN ² ; Sui Kiong LING ² ; See Wan YAN ¹ ; Mee Lee LOOI ³
Author Information

1. School of Biosciences, Taylor's University, Lakeside Campus, 47500 Subang Jaya, Malaysia.
2. Forest Research Institute Malaysia, 52109 Kepong, Malaysia.
3. Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. meelee.looi@um.edu.my.
Publication Type:Journal Article
Keywords: Apoptosis; Cell cycle; Hydroxychavicol (HC); P38 mitogen-activated protein kinase (MAPK); Piper betle; c-Jun N-terminal kinase (JNK)
From: Journal of Zhejiang University. Science. B 2021;22(2):112-122
CountryChina
Language:English
Abstract: This study aims to elucidate the antiproliferative mechanism of hydroxychavicol (HC). Its effects on cell cycle, apoptosis, and the expression of c-Jun N-terminal kinase (JNK) and P38 mitogen-activated protein kinase (MAPK) in HT-29 colon cancer cells were investigated. HC was isolated from