Extraskeletal Ewing sarcoma of thyroid gland: A case report.
10.11817/j.issn.1672-7347.2021.200161
- Author:
Weiyu ZHU
1
;
Xinming YANG
2
;
Junjie ZENG
2
;
Minghui WEI
3
;
Shuang WANG
4
;
Wencheng LI
5
Author Information
1. Department of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116. zhuabinbin@163.com.
2. Department of Otolaryngology, Head and Neck Surgery, Second Xiangya Hospital, Central South University, Changsha 410011.
3. Department of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116.
4. Department of Otolaryngology, Head and Neck Surgery, Second Xiangya Hospital, Central South University, Changsha 410011. wangshuangent@csu.edu.cn.
5. Department of Otolaryngology, Head and Neck Surgery, Anhua People's Hospital, Yiyang Hunan 413500, China.
- Publication Type:Journal Article
- Keywords:
diagnosis;
extraskeletal Ewing sarcoma;
thyroid gland;
treatment
- MeSH:
Adult;
Combined Modality Therapy;
Female;
Humans;
Immunohistochemistry;
Neoplasm Recurrence, Local;
Sarcoma, Ewing/therapy*;
Thyroid Gland
- From:
Journal of Central South University(Medical Sciences)
2021;46(5):558-564
- CountryChina
- Language:English
-
Abstract:
Extraskeletal Ewing sarcoma is a rare event, and extraskeletal Ewing sarcoma of the thyroid gland is even rarer. It has non-specific clinical manifestation and difficulty in early diagnosis. The diagnosis mainly depends on histology and immunohistochemistry. It possesses the features of high malignancy, high rate of local recurrence, and distant metastasis. Currently, the aggressive multimodal treatment contains surgery, chemotherapy, and radiotherapy. This study presented a case of extraskeletal Ewing sarcoma arising in the thyroid gland of a 30-year-old woman, who presented with supraclavicular mass and sense of dysphagia obstruction in Department of Otolaryngology, Head and Neck Surgery, Second Xiangya Hospital, Central South University in 2018. Imaging studies demonstrated a cystic-solid mass in inferior of the left leaf of thyroid gland and in the posterior of the trachea and esophagus. The patient underwent localized tumor resection. The pathological diagnosis revealed that it was a small round cell tumor, and the immunohistochemistry results were considered to be extraskeletal Ewing sarcoma. Subsequently, the patient was given chemotherapy and local radiation therapy. There was no evidence of tumor recurrence or metastasis.
