Clinical characteristics of the patients with asymptomatic primary hyperparathyroidism.
10.11817/j.issn.1672-7347.2021.200356
- Author:
Xiao'ai YAO
1
;
Tao JIANG
2
;
Bojun WEI
3
;
Hong CHANG
4
Author Information
1. Department of Endocrinology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038. yaoxiaoaixin@sina.com.
2. Department of Endocrinology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038. taojiangxin2016@sina.com.
3. Department of Otolaryngology Head and Neck Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038.
4. Department of Pathology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
- Publication Type:Journal Article
- Keywords:
asymptomatic primary hyperparathyroidism;
clinical characteristics;
parathyroid adenoma;
parathyroid carcinoma;
parathyroid hyperplasia
- MeSH:
Calcium;
China/epidemiology*;
Humans;
Hyperparathyroidism, Primary/epidemiology*;
Parathyroid Glands;
Parathyroid Hormone;
Retrospective Studies
- From:
Journal of Central South University(Medical Sciences)
2021;46(4):368-372
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:The prevalence of asymptomatic primary hyperparathyroidism (PHPT) in China is lower than that in European and American countries and the study about the characteristics of asymptomatic PHPT was rare in China. This study aims to explore the characteristics of asymptomatic PHPT.
METHODS:Clinical data of 150 patients with PHPT confirmed by operation and pathological examination were retrospectively analyzed. The patients were assigned into a symptomatic PHPT group (
RESULTS:The proportion of adenomas was higher than that of adenocarcinoma in the asymptomatic PHPT group. The proportion of the first diagnosis due to hypercalcemia found via biochemical examination in the asymptomatic PHPT group was higher than that in the symptomatic PHPT group (76.92% vs 25.81%,
CONCLUSIONS:Only a minority of PHPT patients are asymptomatic. Compared with the symptomatic PHPT patients, the primary cause of diagnosis is hypercalcemia, the duration of diagnosis and the diameter of parathyroid gland are shorter, the levels of serum calcium, and PTH are lower, the proportion of adenomas, vitamin D, and the BMD of L
