Progress in application of near-infrared fluorescence imaging in the diagnosis and treatment of oral cancer.
10.11817/j.issn.1672-7347.2021.190762
- Author:
Huangxing MAO
1
;
Ying LONG
2
;
Xiaowu SHENG
2
;
Xiao ZHOU
3
;
Bo ZHOU
4
Author Information
1. Breast Oncoplastic Surgery Department/ Head and Neck Surgery Department 3, Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410006. 454790112@qq.com.
2. Center for Translational Medicine, Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410006, China.
3. Breast Oncoplastic Surgery Department/ Head and Neck Surgery Department 3, Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410006.
4. Breast Oncoplastic Surgery Department/ Head and Neck Surgery Department 3, Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410006. zhoubo@hnca.org.cn.
- Publication Type:Journal Article
- Keywords:
indocyanine green;
near-infrared fluorescence imaging;
oral cancer
- MeSH:
Humans;
Indocyanine Green;
Lymph Nodes;
Mouth Neoplasms/therapy*;
Optical Imaging;
Sentinel Lymph Node Biopsy
- From:
Journal of Central South University(Medical Sciences)
2021;46(3):316-321
- CountryChina
- Language:English
-
Abstract:
The preliminary screening of oral cancer mostly depends on the experience of clinicians, The surgical margin of tumor is mostly based on physical examination and preoperative imaging examination. It lacks real-time and objective intraoperative evaluation methods. Indocyanine green (ICG), as a safe and pollution-free organic fluorescent pigments, combined with near-infrared fluorescence imaging can be applied in the screening of early oral cancer, the determination of tumor resection margins, sentinel lymph node biopsy, cervical lymph node dissection, targeted chemotherapy, and other aspects. Near-infrared fluorescence imaging may become a key link in the early diagnosis and accurate treatment for oral cancer in the future.
