Clinical and X-ray characteristics for expressions of different receptors in patients with breast cancer.
10.11817/j.issn.1672-7347.2021.190371
- Author:
Xueqing HUANG
1
;
Siqing CAI
2
;
Peili WU
3
;
Shunfa HUANG
3
;
Miaomiao YAO
3
Author Information
1. Department of Imaging, Second Affiliated Hospital of Fujian Medical University, Quanzhou Fujian 362333, China. 834285635@qq.com.
2. Department of Imaging, Second Affiliated Hospital of Fujian Medical University, Quanzhou Fujian 362333, China. 1920455696@qq.com.
3. Department of Imaging, Second Affiliated Hospital of Fujian Medical University, Quanzhou Fujian 362333, China.
- Publication Type:Journal Article
- Keywords:
X-ray characteristics;
breast cancer;
molecular subtype;
receptor
- MeSH:
Biomarkers, Tumor;
Breast Neoplasms/genetics*;
Female;
Humans;
Receptor, ErbB-2/genetics*;
Receptors, Estrogen;
Receptors, Progesterone;
X-Rays
- From:
Journal of Central South University(Medical Sciences)
2021;46(3):263-271
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:Clarifying the expression of breast cancer receptor is the key to clinical treatment for breast cancer. This study aims to explore the correlation between X-ray and clinical characteristics of 4 molecular subtypes and their receptor types of breast cancer.
METHODS:A total of 439 breast cancer patients who confirmed by pathology and performed X-ray examination were enrolled. The X-ray and clinical characteristics of 4 molecular subtypes and the expression of their receptors were analyzed.
RESULTS:Luminal A type showed the highest proportion of spiculate masses, and the lowest calcification score, showing significant difference with other 3 subtypes (all
CONCLUSIONS:Four molecular subtypes of breast cancer and their receptor expressions are correlated with X-ray and clinical characteristics, which can provide a basis for clinical diagnosis and treatment.