Research progress in Lamins in malignant tumors.
10.11817/j.issn.1672-7347.2020.190499
- Author:
Haixiao DENG
1
;
Zeyuan YU
2
;
Jihe KANG
2
;
Junjie QIN
2
;
Xiangyan JIANG
2
;
Zuoyi JIAO
3
Author Information
1. Department of General Surgery, Second Hospital of Lanzhou University, Lanzhou 730000, China. denghx19@lzu.edu.cn.
2. Department of General Surgery, Second Hospital of Lanzhou University, Lanzhou 730000, China.
3. Department of General Surgery, Second Hospital of Lanzhou University, Lanzhou 730000, China. jiaozy@lzu.edu.cn.
- Publication Type:Journal Article
- Keywords:
Lamins;
malignant tumors;
tumor markers
- MeSH:
Cell Nucleus;
Humans;
Lamins/genetics*;
Neoplasms/genetics*;
Prognosis
- From:
Journal of Central South University(Medical Sciences)
2020;45(12):1490-1498
- CountryChina
- Language:English
-
Abstract:
Changes in nuclear morphology are common in malignant tumors, but the underlying molecular mechanisms remain poorly understood. Lamins is involved in supporting nuclear structure, and the expression of Lamins is the molecular basis for nuclear morphological changes during tumor progression. In recent years, the research on the relationship between Lamins and malignant tumors has made great progress. Lamins is of great value in the diagnosis, treatment, and prognosis of various malignant tumors.
