A case of metastatic malignant pheochromocytoma response to high dose 131I-MIBG treatment after surgery.
- Author:
Shin Won LEE
1
;
Jung Guk KIM
;
Sung Woo HA
;
Byeong Cheal AHN
;
Jae Tae LEE
;
Bup Wan KIM
;
Bo Wan KIM
Author Information
1. Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea. swha@knu.ac.kr
- Publication Type:Case Report
- Keywords:
Malingnant pheochromocytoma;
Neoplasm metastasis;
3-Iodobenzylguanidine
- MeSH:
3-Iodobenzylguanidine;
Abdomen;
Blood Vessels;
Headache;
Humans;
Hypertension;
Male;
Middle Aged;
Neoplasm Metastasis;
Pheochromocytoma*;
Plasma;
Reference Values;
Tomography, X-Ray Computed
- From:Korean Journal of Medicine
2004;67(Suppl 3):S871-S875
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Approximately 10% of pheochromocytomas are malignant and its major criteria are tumor invasion of capsular blood vessel as well as metastatic invasion of other tissues. It is general rule that all resectable masses have to be removed surgically. However, there is no definite treatment modality about unresectable masses or microinvasive lesions. We experienced a case of 45 year-old male patient who was referred to our hospital for treatment of hypertension and headache. The plasma and urine catecholamine were increased above normal values and its metabolites also were increased. 131I-metaiodobenzylguanidine (MIBG) scan showed right adrenal mass and metastatic lesion of left iliac bone. This lesion was consistent with findings of the abdomen computed tomography (CT) and electron beam tomography (EBT) scan. We diagnosed this case as malignant pheochromocytoma. We removed primary tumor mass by wide excision and treated this patient with high dose 131I-MIBG. We report this case who shows good response to the high dose 131I-MIBG after surgery.
