Protective Effect of Brassica napus L. Hydrosols against Inflammation Response in RAW 264.7 Cells.
10.1007/s11655-021-3330-9
- Author:
Su-Hyeon CHO
1
;
Song Rae KIM
1
;
Myeong Seon JEONG
1
;
Miri CHOI
1
;
SeonJu PARK
1
;
Kil-Nam KIM
2
Author Information
1. Chuncheon Center, Korea Basic Science Institute, Chuncheon, 24341, Republic of Korea.
2. Chuncheon Center, Korea Basic Science Institute, Chuncheon, 24341, Republic of Korea. knkim@kbsi.re.kr.
- Publication Type:Journal Article
- Keywords:
Brassica napus L.;
RAW 264.7 cells;
hydrosols;
inflammation;
lipopolysaccharide
- From:
Chinese journal of integrative medicine
2021;27(4):273-279
- CountryChina
- Language:English
-
Abstract:
OBJECTIVE:To demonstrate the anti-inflammatory activity of Brassica napus L. hydrosols (BNH) in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells.
METHODS:Composition analysis of BNH was conducted via gas chromatography-mass spectrometry after BNH were extracted. The nitric oxide (NO) production was measured using the Griess assay. Prostaglandin E
RESULTS:Compared with LPS-stimulated cells, BNH markedly decreased the generation of NO and PGE
CONCLUSION:The anti-inflammatory activities of BNH were mediated via blockage of the NF-κB signaling pathways in LPS-stimulated RAW 264.7 cells.
