A Case of Community-acquired Legionnaires' Disease in a Renal Transplant Recipient.
- Author:
Woong SEOG
1
;
Yong Jin JUNG
;
Heung Woo PARK
;
Hae Kyung LEE
;
Man Suck PARK
;
Mi Yeoun PARK
;
Kyung Seok PARK
;
Myoung Don OH
;
Curie AHN
;
Eui Chong KIM
;
Kang Won CHOE
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Legionella;
Pneumonia;
Transplantation
- MeSH:
Asymptomatic Infections;
Chills;
Cyclosporine;
Diagnosis, Differential;
DNA;
Dyspnea;
Fever;
Humans;
Immunocompromised Host;
Kidney Transplantation;
Legionella;
Legionella pneumophila;
Legionnaires' Disease*;
Lung;
Middle Aged;
Physical Examination;
Pneumonia;
Polymerase Chain Reaction;
Radiography, Thoracic;
Respiratory Sounds;
Roxithromycin;
Serologic Tests;
Transplantation*
- From:Korean Journal of Infectious Diseases
1999;31(4):353-357
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Legionella species are causative agents of both community-acquired and nosocomial pneumonia. The spectrum of disease ranges from asymptomatic infection to serious disease and two specific syndromes are identified, i.e., Legionnaires' disease and Pontiac fever. Legionnaires' disease tends to occur in patients with underlying illnesses, so Legionella pneumonia should be included in the differential diagnosis of severe community-acquired pneumonia, especially in immunocompromised patients. Herein we report a case of community- acquired Legionnaires' disease in a patient with renal transplantation. A 63-year old man was admitted because of fever, chills, and dyspnea. Thirteen years ago, he had undergone kidney transplantation and he had received immu-nosuppressive agents, including deflazacort and cyclosporin A. On physical examination crackles were heard in the middle area of the right lung and the chest radiograph showed multifocal patchy consolidations on both lung fields. Serologic tests for Legionella pneumophila antibody, urinary antigen assay for L. pneumophila serogroup 1, and polymerase chain reaction for Legionella DNA fragments (5S rRNA, IPC, mip target sequence) were positive. The patient was treated with roxithromycin for twenty eight days and recovered without complication.
