Design of Detection Module in Coagulometers Based on Dual-magnetic Circuit Beads Method.
10.3969/j.issn.1671-7104.2021.02.006
- Author:
Shaomin LI
1
;
Xingwei ZHANG
1
;
Junfang QIN
2
;
Yongjie ZHAO
1
;
Zhaohong XIE
1
;
Xinjian LU
3
;
Qihao LIU
1
Author Information
1. Shantou University, Shantou, 515063.
2. Guangzhou Excbio Technology Co. Ltd., Guangzhou, 510663.
3. Guangdong Goldenwork Robot Technology Co. Ltd., Foshan, 528226.
- Publication Type:Journal Article
- Keywords:
blood coagulation analyzer;
coagulation detection principle;
dual-magnetic circuit beads method
- MeSH:
Blood Coagulation;
Blood Coagulation Tests;
Magnetic Phenomena;
Magnetics;
Partial Thromboplastin Time
- From:
Chinese Journal of Medical Instrumentation
2021;45(2):145-152
- CountryChina
- Language:Chinese
-
Abstract:
Coagulometer, known as blood coagulation analyzer, is a product that can provide accurate test results for medical diagnosis and treatment analysis by detecting a series of items closely related to thrombosis and hemostasis in coagulation reaction. On the basis of previous traditional methods, and with our deep understanding about the principles of hemagglutination detection, we propose a hemagglutination detection method by using the dual-magnetic circuit beads method. Then, the corresponding hemagglutination detection module is designed. The coagulation time of plasma can be measured by detecting the movement of the magnetic beads when the magnetic field intensity is appropriate. The activated partial thromboplastin time(APTT) of plasma is tested when the most suitable magnetic field intensity is found. The results preliminarily show that this blood coagulation test method is valid and the corresponding test module has a potential value in business.
