Advances in Preparation and Evaluation of Non-vascular Drug-eluting Stents.
10.3969/j.issn.1671-7104.2021.01.010
- Author:
Yu GAN
1
;
Cong WEN
2
;
Fang JIN
3
;
Hua ZHU
4
Author Information
1. Yangzhou University Medical Academy, Yangzhou, 225009.
2. Shanghai Frontier Health Pharmaceutical Technology Co. Ltd, Shanghai, 200120.
3. Guangzhou Joincare Respiratory Medicine Co. Ltd, Guangzhou, 510530.
4. Jiangsu Subei People's Hospital Affiliated to Medical School, Yangzhou University, Yangzhou, 225001.
- Publication Type:Journal Article
- Keywords:
drug-eluting stent;
interventional therapy;
non-vascular;
preparation and evaluation
- MeSH:
Coronary Restenosis;
Drug-Eluting Stents;
Humans;
Prosthesis Design;
Treatment Outcome
- From:
Chinese Journal of Medical Instrumentation
2021;45(1):46-51
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the application of stent intervention in the treatment of non-vascular stenosis caused by benign and malignant factors has been widely concerned by researchers at home and abroad. The high incidence of malignant tumor diseases, further promotes the development of stent intervention. The conventional bare stents are prone to irritate luminal mucosa and produce restenosis and other complications. The emergence of drug-eluting stent is expected to solve this problem and become one of the important development trends of non-vascular stents. In this paper, the drug loading materials, drug loading layer drugs, preparation technology and quality evaluation methods of non-vascular drugeluting stent are described based on the recent research and clinical application documents, so as to provide basis and direction for the follow-up research and development.