Development of Liver Normothermic Machine Perfusion Repair and Assessment System.
10.3969/j.issn.1671-7104.2021.01.008
- Author:
Wenyan LIU
1
;
Fengfeng LIU
2
;
Yi LYU
3
;
Bo TANG
3
;
Tao MA
3
;
Yang YAN
2
;
Yunqiao ZHENG
4
;
Xinglong ZHENG
3
Author Information
1. Department of Blood Purification, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061.
2. Department of Cardiovascular Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061.
3. First Affiliated Hospital of Xi'an Jiaotong University, National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi'an, 710061.
4. Department of Operation and Anesthesia, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061.
- Publication Type:Journal Article
- Keywords:
assessment of donor liver;
normothermic machine perfusion;
preservation of donor liver
- MeSH:
Humans;
Liver;
Liver Transplantation;
Living Donors;
Organ Preservation;
Perfusion
- From:
Chinese Journal of Medical Instrumentation
2021;45(1):37-41
- CountryChina
- Language:Chinese
-
Abstract:
This paper introduced a liver normothermic machine perfusion repair and assessment system. This system consists of a liver normothermic machine perfusion device, a fluorescence imaging system and a tissue oxygen detector. The normothermic machine perfusion device can continuously perfuse the donor liver and monitor and control the perfusion parameters in real time. The fluorescence imaging system can detect the indocyanine green metabolized by the liver to evaluate the microcirculation and the metabolism function of hepatocytes. The tissue oxygen detector can monitor the change of oxygen partial pressure of liver tissue in real time to evaluate the state of cell oxygen consumption.
