Determinants of bone health in elderly Japanese men: study design and key findings of the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) cohort study.

Yuki Fujita; Junko Tamaki; Katsuyasu Kouda; Akiko Yura; Yuho Sato; Takahiro Tachiki; Masami Hamada; Etsuko Kajita; Kuniyasu Kamiya; Kazuki Kaji; Koji Tsuda; Kumiko Ohara; Jong-seong Moon; Jun Kitagawa; Masayuki Iki

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Determinants of bone health in elderly Japanese men: study design and key findings of the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) cohort study.

Author: Yuki FUJITA ¹ ; Junko TAMAKI ² ; Katsuyasu KOUDA ³ ; Akiko YURA ¹ ; Yuho SATO ⁴ ; Takahiro TACHIKI ⁵ ; Masami HAMADA ⁵ ; Etsuko KAJITA ⁵ ; Kuniyasu KAMIYA ² ; Kazuki KAJI ⁶ ; Koji TSUDA ² ; Kumiko OHARA ¹ ; Jong-Seong MOON ⁷ ; Jun KITAGAWA ⁸ ; Masayuki IKI ⁹
Author Information

1. Department of Public Health, Kindai University Faculty of Medicine, 377-2 Oono-higashi, Osaka-Sayama, Osaka, 589-8511, Japan.
2. Department of Hygiene and Public Health, Osaka Medical and Pharmaceutical University, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan.
3. Department of Hygiene and Public Health, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan.
4. Department of Human Life, Jin-ai University, 3-1-1 Ootemachi, Echizen, Fukui, 915-8586, Japan.
5. Faculty of Nursing, Chukyo Gakuin University, 2216 Tokicho, Mizunami, Gifu, 509-6192, Japan.
6. Department of Rehabilitation, Kitasato University Kitasato Institute Hospital, Minato Ward, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8642, Japan.
7. Department of Nursing, Kio University, 4-2-2 Umami-naka, Koryo-cho, Nara, 635-0832, Japan.
8. Department of Rehabilitation Sciences, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Sagamihara, Kanagawa, 252-0373, Japan.
9. Department of Public Health, Kindai University Faculty of Medicine, 377-2 Oono-higashi, Osaka-Sayama, Osaka, 589-8511, Japan. masa@med.kindai.ac.jp.
Collective Name:FORMEN study group
Publication Type:Journal Article
Keywords: Bone mineral density; Bone turnover marker; Bone-multiorgan crosstalk; Community-dwelling Japanese elderly men; Death; Fracture; Osteoporosis; Quality of life; Risk model
MeSH: Aged; Bone Density; Cardiovascular Diseases/etiology*; Cohort Studies; Geriatric Assessment; Humans; Independent Living; Japan/epidemiology*; Long-Term Care/statistics & numerical data*; Male; Middle Aged; Osteoporosis/etiology*; Osteoporotic Fractures/etiology*; Risk Factors
From:Environmental Health and Preventive Medicine 2021;26(1):51-51
CountryJapan
Language:English
Abstract: BACKGROUND:The Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study was launched to investigate risk factors for osteoporotic fractures, interactions of osteoporosis with other non-communicable chronic diseases, and effects of fracture on QOL and mortality.
METHODS:FORMEN baseline study participants (in 2007 and 2008) included 2012 community-dwelling men (aged 65-93 years) in Nara prefecture, Japan. Clinical follow-up surveys were conducted 5 and 10 years after the baseline survey, and 1539 and 906 men completed them, respectively. Supplemental mail, telephone, and visit surveys were conducted with non-participants to obtain outcome information. Survival and fracture outcomes were determined for 2006 men, with 566 deaths identified and 1233 men remaining in the cohort at 10-year follow-up.
COMMENTS:The baseline survey covered a wide range of bone health-related indices including bone mineral density, trabecular microarchitecture assessment, vertebral imaging for detecting vertebral fractures, and biochemical markers of bone turnover, as well as comprehensive geriatric assessment items. Follow-up surveys were conducted to obtain outcomes including osteoporotic fracture, cardiovascular diseases, initiation of long-term care, and mortality. A complete list of publications relating to the FORMEN study can be found at https://www.med.kindai.ac.jp/pubheal/FORMEN/Publications.html .