Associations between trunk-to-peripheral fat ratio and cardiometabolic risk factors in elderly Japanese men: baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study.
10.1186/s12199-021-00959-9
- Author:
Katsuyasu KOUDA
1
;
Yuki FUJITA
2
;
Kumiko OHARA
2
;
Takahiro TACHIKI
3
;
Junko TAMAKI
4
;
Akiko YURA
2
;
Jong-Seong MOON
5
;
Etsuko KAJITA
3
;
Kazuhiro UENISHI
6
;
Masayuki IKI
2
Author Information
1. Department of Hygiene and Public Health, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan. koudakat@hirakata.kmu.ac.jp.
2. Department of Public Health, Kindai University Faculty of Medicine, 377-2 Oono-higashi, Osaka-Sayama, Osaka, 589-8511, Japan.
3. Chukyo Gakuin University Faculty of Nursing, 2216 Tokicho, Mizunami, Gifu, 509-6192, Japan.
4. Department of Hygiene and Public Health, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan.
5. Department of Nursing, Kio University, 4-2-2 Umami-naka, Koryo-cho, Nara, 635-0832, Japan.
6. Laboratory of Physiological Nutrition, Kagawa Nutrition University, 3-9-21 Chiyoda, Sakado, Saitama, 350-0288, Japan.
- Publication Type:Journal Article
- Keywords:
Body fat distribution;
Densitometry;
Epidemiology;
Risk factors
- MeSH:
Absorptiometry, Photon;
Adiposity/physiology*;
Aged;
Aged, 80 and over;
Biomarkers/metabolism*;
Cardiometabolic Risk Factors;
Cross-Sectional Studies;
Humans;
Intra-Abdominal Fat/diagnostic imaging*;
Japan;
Male;
Osteoporosis/etiology*;
Prospective Studies;
Risk Assessment;
Risk Factors;
Thorax/diagnostic imaging*
- From:Environmental Health and Preventive Medicine
2021;26(1):35-35
- CountryJapan
- Language:English
-
Abstract:
BACKGROUND:Body mass-independent parameters might be more appropriate for assessing cardiometabolic abnormalities than weight-dependent indices in Asians who have relatively high visceral adiposity but low body fat. Dual-energy X-ray absorptiometry (DXA)-measured trunk-to-peripheral fat ratio is one such body mass-independent index. However, there are no reports on relationships between DXA-measured regional fat ratio and cardiometabolic risk factors targeting elderly Asian men.
METHODS:We analyzed cross-sectional data of 597 elderly men who participated in the baseline survey of the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study, a community-based single-center prospective cohort study conducted in Japan. Whole-body fat and regional fat were measured with a DXA scanner. Trunk-to-appendicular fat ratio (TAR) was calculated as trunk fat divided by appendicular fat (sum of arm and leg fat), and trunk-to-leg fat ratio (TLR) as trunk fat divided by leg fat.
RESULTS:Both TAR and TLR in the group of men who used ≥ 1 medication for hypertension, dyslipidemia, or diabetes ("user group"; N = 347) were significantly larger than those who did not use such medication ("non-user group"; N = 250) (P < 0.05). After adjusting for potential confounding factors including whole-body fat, both TAR and TLR were significantly associated with low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglyceride, fasting serum insulin, and the insulin resistance index in the non-user group and non-overweight men in the non-user group (N = 199).
CONCLUSION:The trunk-to-peripheral fat ratio was associated with cardiometabolic risk factors independently of whole-body fat mass. Parameters of the fat ratio may be useful for assessing cardiometabolic risk factors, particularly in underweight to normal-weight populations.
