Outdoor air pollution and diminished ovarian reserve among infertile Korean women.
10.1186/s12199-021-00942-4
- Author:
Hannah KIM
1
;
Seung-Ah CHOE
2
;
Ok-Jin KIM
3
;
Sun-Young KIM
3
;
Seulgi KIM
4
;
Changmin IM
5
;
You Shin KIM
1
;
Tae Ki YOON
1
Author Information
1. Department of Obstetrics and Gynecology, CHA Fertility Center Seoul Station, CHA University School of Medicine, Seoul, 04637, Korea.
2. Department of Obstetrics and Gynecology, CHA Fertility Center Seoul Station, CHA University School of Medicine, Seoul, 04637, Korea. seungah@korea.ac.kr.
3. Department of Cancer Control and Population Health, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang-si, Gyeonggi-do, 10408, Korea.
4. Department of Public Health Science, Graduate School of Public Health, Seoul National University, Seoul, 08826, Korea.
5. Department of Geography, Korea University, Seoul, 02841, South Korea.
- Publication Type:Journal Article
- Keywords:
Air pollution;
Anti-Müllerian hormone;
Fertility;
Ovarian reserve
- MeSH:
Adult;
Air Pollutants/adverse effects*;
Air Pollution/adverse effects*;
Environmental Exposure/adverse effects*;
Female;
Humans;
Infertility, Female/etiology*;
Ovarian Reserve/physiology*;
Republic of Korea
- From:Environmental Health and Preventive Medicine
2021;26(1):20-20
- CountryJapan
- Language:English
-
Abstract:
BACKGROUND:Mounting evidence implicates an association between ambient air pollution and impaired reproductive potential of human. Our study aimed to assess the association between air pollution and ovarian reserve in young, infertile women.
METHODS:Our study included 2276 Korean women who attended a single fertility center in 2016-2018. Women's exposure to air pollution was assessed using concentrations of particulate matter (PM
RESULTS:The mean age was 36.6 ± 4.2 years and AMH level was 3.3 ± 3.1 ng/mL in the study population. Average AMH ratio was 0.8 ± 0.7 and low AMH was observed in 10.3% of women (n=235). The average concentration of six air pollutants was not different between the normal ovarian reserve and low AMH groups for all averaging periods. In multivariable models, an interquartile range (IQR)-increase in 1 month-average PM
CONCLUSIONS:In a cohort of infertile Korean women, there was a suggestive evidence of the negative association between ambient PM concentration and ovarian reserve, highlighting the potential adverse impact of air pollution on women's fertility.
