Effects of exposure to low-dose ionizing radiation on changing platelets: a prospective cohort study.
10.1186/s12199-021-00939-z
- Author:
Ning LIU
1
;
Yang PENG
2
;
Xinguang ZHONG
3
;
Zheng MA
4
;
Suiping HE
1
;
Ying LI
1
;
Wencui ZHANG
1
;
Zijun GONG
1
;
Zhenjiang YAO
5
Author Information
1. Department of Epidemiology and Health Statistics, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, 510310, Guangdong, China.
2. Cancer Research Centre, Cancer Council Queensland, Fortitude Valley, Brisbane, 4006, Australia.
3. The Sixth People's Hospital of Dongguan, Dongguan, 532008, Guangdong, China. zxgcdc@qq.com.
4. The Sixth People's Hospital of Dongguan, Dongguan, 532008, Guangdong, China.
5. Department of Epidemiology and Health Statistics, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, 510310, Guangdong, China. zhjyao2001@yahoo.com.
- Publication Type:Journal Article
- Keywords:
Hematological;
Low-dose ionizing radiation;
Occupation exposure;
Platelets
- MeSH:
Adult;
Aged;
Blood Platelets/radiation effects*;
Female;
Health Personnel/statistics & numerical data*;
Humans;
Male;
Middle Aged;
Occupational Exposure/adverse effects*;
Prospective Studies;
Radiation Dosage;
Radiation Exposure/adverse effects*;
Radiation, Ionizing;
Young Adult
- From:Environmental Health and Preventive Medicine
2021;26(1):14-14
- CountryJapan
- Language:English
-
Abstract:
BACKGROUND:Numerous studies have concentrated on high-dose radiation exposed accidentally or through therapy, and few involve low-dose occupational exposure, to investigate the correlation between low-dose ionizing radiation and changing hematological parameters among medical workers.
METHODS:Using a prospective cohort study design, we collected health examination reports and personal dose monitoring data from medical workers and used Poisson regression and restricted cubic spline models to assess the correlation between changing hematological parameters and cumulative radiation dose and determine the dose-response relationship.
RESULTS:We observed that changing platelet of 1265 medical workers followed up was statistically different among the cumulative dose groups (P = 0.010). Although the linear trend tested was not statistically significant (P
CONCLUSION:We concluded that although the exposure dose was below the limit, medical workers exposed to low-dose ionizing radiation for a short period of time might have increased first and then decreased platelets, and there was a dose-response relationship between the cumulative radiation dose and platelets changing.
