Resveratrol inhibits Ca
10.1186/s12199-020-00905-1
- Author:
Mikio MARUMO
1
;
Kazumi EKAWA
1
;
Ichiro WAKABAYASHI
2
Author Information
1. Department of Environmental and Preventive Medicine, Hyogo College of Medicine, Mukogawa-cho 1-1, Nishinomiya, Hyogo, 663-8501, Japan.
2. Department of Environmental and Preventive Medicine, Hyogo College of Medicine, Mukogawa-cho 1-1, Nishinomiya, Hyogo, 663-8501, Japan. wakabaya@hyo-med.ac.jp.
- Publication Type:Journal Article
- Keywords:
Ca2+channels;
Inositol trisphosphate;
Platelet aggregation;
Resveratrol;
Store-operated Ca2+influx
- MeSH:
Antioxidants/administration & dosage*;
Calcium/physiology*;
Humans;
Platelet Aggregation/drug effects*;
Platelet Aggregation Inhibitors/pharmacology*;
Resveratrol/pharmacology*;
Signal Transduction/drug effects*
- From:Environmental Health and Preventive Medicine
2020;25(1):70-70
- CountryJapan
- Language:English
-
Abstract:
BACKGROUND:Resveratrol has been shown to inhibit platelet aggregation. However, the mechanism for this action of resveratrol remains to be clarified. The purpose of this study was to elucidate the Ca
METHODS:Ca
RESULTS:Thapsigargin-induced Ca
CONCLUSIONS:The results suggest that resveratrol inhibits thrombin-induced platelet aggregation through decreasing Ca
