PM
10.1186/s12199-020-00909-x
- Author:
Ying-Hsiang CHOU
1
;
Disline Manli TANTOH
2
;
Ming-Chi WU
2
;
Yeu-Sheng TYAN
3
;
Pei-Hsin CHEN
4
;
Oswald Ndi NFOR
4
;
Shu-Yi HSU
4
;
Chao-Yu SHEN
5
;
Chien-Ning HUANG
6
;
Yung-Po LIAW
7
Author Information
1. Institute of Medicine, Chung Shan Medical University, Taichung City, 40201, Taiwan.
2. Department of Medical Imaging, Chung Shan Medical University Hospital, No. 110, Sec. 1 Jianguo N. Rd, Taichung City, 40201, Taiwan.
3. School of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung City, 40201, Taiwan.
4. Department of Public Health and Institute of Public Health, Chung Shan Medical University, No. 110, Sec. 1 Jianguo N. Rd, Taichung City, 40201, Taiwan.
5. School of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung City, 40201, Taiwan. shenchaoyu@gmail.com.
6. Institute of Medicine, Chung Shan Medical University, Taichung City, 40201, Taiwan. cshy049@gami.com.
7. Department of Medical Imaging, Chung Shan Medical University Hospital, No. 110, Sec. 1 Jianguo N. Rd, Taichung City, 40201, Taiwan. Liawyp@csmu.edu.tw.
- Publication Type:Journal Article
- Keywords:
DLEC1;
Exercise;
Methylation;
PM2.5;
Taiwan Biobank
- MeSH:
Adult;
Aged;
Air Pollutants/adverse effects*;
DNA Methylation/drug effects*;
Environmental Exposure/adverse effects*;
Exercise;
Female;
Humans;
Male;
Middle Aged;
Particulate Matter/adverse effects*;
Taiwan;
Tumor Suppressor Proteins/metabolism*
- From:Environmental Health and Preventive Medicine
2020;25(1):68-68
- CountryJapan
- Language:English
-
Abstract:
BACKGROUND:Particulate matter (PM) < 2.5 μm (PM
METHODS:We obtained DNA methylation and exercise data of 496 participants (aged between 30 and 70 years) from the Taiwan Biobank (TWB) database. We also extracted PM
RESULTS:DLEC1 methylation and PM
CONCLUSIONS:We found significant positive associations between PM
