Research Progress of Circular RNA in Lung Cancer.
10.3779/j.issn.1009-3419.2020.102.38
- Author:
Xiangwei GE
1
;
Zhibo ZHANG
1
;
Xiaoyu ZHI
1
;
Jinliang WANG
1
Author Information
1. Department of Oncology, the First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
- Publication Type:Journal Article
- Keywords:
Circular RNA;
Diagnosis;
Lung neoplasms;
Prognosis;
Treatment
- From:
Chinese Journal of Lung Cancer
2020;23(12):1095-1100
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer is the most common malignant tumor with the highest morbidity and mortality worldwide, and its imposes an insupportable burden on patients due to its poor prognosis. The diagnosis and treatment of lung cancer is under great pressure. Therefore, it is urgent to explore effective therapeutic targets and molecular markers. Circular RNA (circRNA) is a kind of covalently closed non-coding RNAs, which has attracted much attention due to its conservation, stability and tissue specificity. Many studies have found that circRNA participates in the regulation of lung cancer through various mechanisms such as sponging miRNA and plays a part vital role in the early diagnosis, treatment and prognosis evaluation. In recent years, there have been numerous studies on circRNA in lung cancer. This paper summarizes the current progress of circRNA in the diagnosis, treatment and prognosis of lung cancer.
.
