Pathological and Molecular Features of Lung Micropapillary Adenocarcinoma.
10.3779/j.issn.1009-3419.2020.102.37
- Author:
Jiafeng LIANG
1
;
Qiong WU
1
;
Shenglin MA
1
;
Shirong ZHANG
1
Author Information
1. Translational Medicine Research Center, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine,
Hangzhou 310006, China.
- Publication Type:Journal Article
- Keywords:
Driver gene;
Immune microenvironment;
Metastasis;
Micropapillary adenocarcinoma;
Recurrence
- From:
Chinese Journal of Lung Cancer
2020;23(11):1007-1013
- CountryChina
- Language:Chinese
-
Abstract:
Lung micropapillary adenocarcinoma is characterized by frequent metastasis, lymph node infiltration, high recurrence rate and low overall survival rate as a high-grade lung adenocarcinoma. Special oncogenic pathway is activated and immune microenvironment is established in this subtype of tumor. This article reviews the Pathological phenomena and molecular features of micropapillary adenocarcinoma studied in recent years, aiming to deepen the understanding of micropapillary lesions and lay the foundation for formulating specific treatment strategies.
.