Genetic Polymorphism of Antigens in Twelve Rare Blood Group Systems of Li Nationality in Hainan Province.
10.19746/j.cnki.issn.1009-2137.2021.03.042
- Author:
Xiao-Ling FU
1
;
Xing-Quan CAI
2
;
Shi-Ping YANG
3
;
Bin WU
4
;
Li-Ni WU
5
;
Xing-Dan ZHAO
1
;
Ai-Han WENG
1
;
Lan XIA
6
Author Information
1. Department of Blood Transfusion, Hainan Women and Children's Medical Center, Haikou 570311, Hainan Province, China.
2. Department of Blood Transfusion,Hainan General Hospital, Haikou 570311, Hainan Province, China.
3. Department of Radiation Oncology，Hainan General Hospital, Haikou 570311, Hainan Province, China.
4. Department of Medical Administration，Hainan General Hospital, Haikou 570311, Hainan Province, China.
5. Department of Blood Transfusion，Hainan General Hospital, Haikou 570311, Hainan Province, China.
6. Department of Blood Transfusion，Hainan General Hospital, Haikou 570311, Hainan Province, China,E-mail:13876066178@163.com.
- Publication Type:Journal Article
- MeSH:
Blood Group Antigens/genetics*;
Ethnic Groups;
Gene Frequency;
Genotype;
Humans;
Kidd Blood-Group System;
Polymorphism, Genetic
- From:
Journal of Experimental Hematology
2021;29(3):917-923
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the distribution characteristics of main antigen gene frequencies of Duffy,Diego,Kidd,Dombrock,MNS,Lutheran,Kell,Colton,Scianna,Yt,Knops and Indian in red blood cell blood group system of Li nationality in Hainan Province.
METHODS:Antigens in twelve rare blood group systems of 214 Li people in Hainan Province were genotyped and analyzed by polymerase chain reaction-sequence specific primers (PCR-SSP).
RESULTS:The gene frequency of antigens in twelve rare blood group systems of 214 Li people in Hainan Province including: the gene frequency of Duffy blood group system: fy
CONCLUSION:The genetic distribution and genetic status in twelve rare blood group systems of Li nationality in Hainan Province are relatively stable. The gene distribution of Duffy, Diego, Kidd, Drombrock, MNS and Lutheran blood group systems are polymorphic and show unique distribution characteristics compared with other regions and different nationalities. The gene frequency distribution of Kell、Colton、Scianna、Yt、Knops、Indian blood group systems are monomorphic.
