Clinical Characteristics and Risk Factors of Nosocomial Infection in 472 Patients with Non-Hodgkin Lymphoma.
10.19746/j.cnki.issn.1009-2137.2021.03.016
- Author:
Xiu-Huan DU
1
;
Xue-Ya ZHANG
2
;
Xiao-Rong LIN
1
;
Qiao-Ling LIU
1
;
Geng TAO
1
;
Ping LIN
1
Author Information
1. Department of Laboratorial Medicine,The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, Fujian Province, China.
2. Department of Hematology,The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, Fujian Province, China,E-mail: jakey3456@sina.com.
- Publication Type:Journal Article
- MeSH:
Cross Infection/epidemiology*;
Drug Resistance, Bacterial;
Humans;
Lymphoma, Non-Hodgkin;
Methicillin-Resistant Staphylococcus aureus;
Retrospective Studies;
Risk Factors
- From:
Journal of Experimental Hematology
2021;29(3):751-756
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the clinical characteristics and risk factors of nosocomial infection in patients with non-Hodgkin lymphoma (NHL), in order to guide better clinical prevention and treatment of nosocomial infection.
METHODS:The incidence of nosocomial infection, infection site, characteristics of pathogenic bacteria, drug sensitivity test results and infection risk factors of 472 non-Hodgkin lymphoma patients admitted to the Second Affiliated Hospital of Fujian Medical University from January 2015 to September 2020 were retrospectively analyzed.
RESULTS:Among the 472 patients, 97 (20.6%) had nosocomial infection, mainly in the lower respiratory tract (41.2%), followed by oral cavity, upper respiratory tract, urogenital tract, and blood. A total of 71 strains of pathogenic bacteria were isolated, including Gram-negative (G
CONCLUSION:NHL patients show high nosocomial infection rate and lower respiratory tract infection is common. Hospital day, clinical stage, presence of bone marrow invasion, and neutrophil count in peripheral blood are independent risk factors.
