Research Advances in Plasticity of Biological Characteristics of Mesenchymal Stem Cells--Review.
10.19746/j.cnki.issn.1009-2137.2021.02.051
- Author:
Pei-Lin LI
1
;
Heng ZHU
2
Author Information
1. Beijing Institute of Radiation Medicine, Beijing 100850, China.
2. Beijing Institute of Radiation Medicine, Beijing 100850, China,E-mail: zhudingdingabc@163.com.
- Publication Type:Review
- MeSH:
Mesenchymal Stem Cell Transplantation;
Mesenchymal Stem Cells;
Wound Healing
- From:
Journal of Experimental Hematology
2021;29(2):629-632
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cells (MSC) are capable of supporting hematopoiesis, regulating immune responses, promoting tissue regeneration and homing to damaged tissues, but their efficacy cannot completely exploit due to various factors. Studies in recent years have shown that the biological characteristics of mesenchymal stem cells have plasticity. Researchers can enhance the biological performance of MSC by pretreatment with hypoxia, bioactive molecules, genetic modification, and mechanical stimulation, as well as adjusting MSC transplantation strategies, which has great significance for promoting the transformation of MSC. Therefore, in this review, the recent research advances in the plasticity of the biological characteristics of MSC are summarized briefly.
