Significance of Tim-3 in The Imbalance of Th17/Treg in Patients with Multiple Myeloma.
10.19746/j.cnki.issn.1009-2137.2021.01.018
- Author:
Rui ZHANG
1
;
Nan-Nan PANG
1
;
Jian-Hua QU
2
Author Information
1. Center of Hematologic Diseases. The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China.
2. Center of Hematologic Diseases. The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China,E-mail：jhuaqu@163.com.
- Publication Type:Journal Article
- MeSH:
Cytokines;
Hepatitis A Virus Cellular Receptor 2;
Humans;
Multiple Myeloma;
T-Lymphocytes, Regulatory;
Th17 Cells
- From:
Journal of Experimental Hematology
2021;29(1):109-114
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the singnificance of Tim-3 in Th17/Treg balance in patients with multiple myeloma (MM).
METHODS:Fifty-six newly diagnosed MM patients and 30 healthy people were enrolled. Flow cytometry was used to detect the expression of Tim-3 on CD4
RESULTS:Compared with the control group, the expression of Tim-3 on CD4
CONCLUSION:The ratios of Th17/Treg, IL-17/IL-10 and Tim-3
