The Predict Significance of ALDH Activity to the Relapse of t(8;21) Acute Myeloid Leukemia Patients at Complete Remission.
10.19746/j.cnki.issn.1009-2137.2021.01.007
- Author:
Lu YANG
1
;
Feng-Ting DAO
1
;
Ya-Zhe WANG
1
;
Yan-Rong LIU
1
;
Hao JIANG
1
;
Qian JIANG
1
;
Kai-Yan LIU
1
;
Ya-Zhen QIN
2
Author Information
1. Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing 100044, China.
2. Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing 100044, China,E-mail: qin2000@aliyun.com.
- Publication Type:Journal Article
- MeSH:
ADP-ribosyl Cyclase 1;
Antigens, CD34;
Flow Cytometry;
Humans;
Leukemia, Myeloid, Acute;
Neoplastic Stem Cells;
Prognosis;
Recurrence;
Remission Induction
- From:
Journal of Experimental Hematology
2021;29(1):43-48
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the predict significance of the high aldehyde dehydrogenase activity (ALDH
METHODS:Bone marrow samples of 23 t(8;21) AML patients diagnosis and achieved complete remission in our hospital from April 2015 to June 2016 were collected, then flow cytometry method was used to detect the activity of ALDH, relationship between it and relapse was analyzed.
RESULTS:All the patients were followed up for a median of 32 (2-52) months. The median percentage of CD34
CONCLUSION:The percentage of CD34
