Expression of Costimulatory Molecule Tim3 on NK Cells and Its Subsets in Patients with Acute Myeloid Leukemia.
10.19746/j.cnki.issn.1009-2137.2020.06.018
- Author:
Wen-Hui WU
1
;
Jian-Wei SHAO
2
;
Yong-Lin JIANG
3
Author Information
1. Department of Laboratory Medicine, Yixing Traditional Chinese Medicine Hospital Wuxi 214200, Jiangsu Province, China,E-mial: ranm3604356@126.com.
2. Department of Laboratory Medicine, Yixing People's Hospital, Wuxi 214200, Jiangsu Province, China.
3. Department of Laboratory Medicine, The Second People's Hospital of Yixing City, Wuxi 214200, Jiangsu Province, China.
- Publication Type:Journal Article
- MeSH:
CD56 Antigen;
Flow Cytometry;
Hepatitis A Virus Cellular Receptor 2;
Humans;
Killer Cells, Natural;
Leukemia, Myeloid, Acute;
Patients
- From:
Journal of Experimental Hematology
2020;28(6):1899-1903
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the expression of costimulatory molecule Tim3 and its subsets on NK cells in patients with acute myeloid leukemia.
METHODS:30 patients with acute myeloid leukemia treated in our hospital from August 2016 to August 2018 were randomly selected as the AML group, and 30 healthy persons in our hospital during the same period were randomly selected as the control group. The expression levels of CD56
RESULTS:The expression levels of CD56
CONCLUSION:The expression of costimulatory molecule Tim3 in NK cells and its subsets of patients with acute myeloid leukemia is down-regulated.
