Research progress on Melkersson-Rosenthal syndrome.
10.3724/zdxbyxb-2021-0103
- Author:
Xiaobo LUO
1
;
Jiongke WANG
1
;
Xin ZENG
1
;
Wenjing KUANG
1
Author Information
1. Department of Oral Medicine.
- Publication Type:Review
- Keywords:
Diagnosis;
Etiology;
Melkersson-Rosenthal syndrome;
Pathology;
Rare diseases;
Review;
Therapy
- MeSH:
Adrenal Cortex Hormones;
Diagnosis, Differential;
Humans;
Lip;
Melkersson-Rosenthal Syndrome/drug therapy*;
Skin;
Young Adult
- From:
Journal of Zhejiang University. Medical sciences
2021;50(2):148-154
- CountryChina
- Language:English
-
Abstract:
Melkersson-Rosenthal syndrome (MRS) is a rare neuro-muco-cutaneous syndrome, which is characterized by recurrent orofacial swelling, recurrent facial paralysis and fissured tongue. It has a high prevalence in young adults. Up to now, the etiology of MRS is still not clear, it may related to infection, immune deficiency and hereditary factors. The pharmacological therapy and surgery are the main treatment. Corticosteroids seems to be the drug of choice for MRS patient, but the specific dosage and therapeutic effect have not yet been determined. Surgeries of lips provide excellent results in persistentlip edema MRS cases. This article reviews the research progress on MRS, focusing on its epidemiology, etiology, histopathological characteristics, clinical manifestations, classification, diagnostic criteria, differential diagnosis and treatment, to provide information for its early diagnosis and appropriate treatment.
