Effect of dexamethasone on the expression of Dynein heavy chain and Dynactin in the cytoplasm of fetal rat cerebral cortical neurons cultured
- Author:
Lin CHENG
1
;
Zi-Yun XIE
1
;
Jian LI
;
Tao BO
1
Author Information
1. Department of Pediatrics, Third Xiangya Hosptial, Central South University, Changsha 410011, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Cytoplasm;
Dexamethasone/pharmacology*;
Dynactin Complex/genetics*;
Dyneins;
Neurons;
Rats
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(6):639-644
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the effect of dexamethasone (DEX) on the expression of Dynein heavy chain (DHC) and Dynactin in the cytoplasm of fetal rat cerebral cortical neurons cultured
METHODS:Primary cerebral cortical neurons of fetal rats were cultured
RESULTS:There was no significant difference in the mRNA expression levels of DHC and Dynactin among the three groups at all time points (
CONCLUSIONS:DEX affects the protein expression of DHC and Dynactin in the fetal rat cerebral cortical neurons cultured
