Clinical features of very preterm infants with prelabor rupture of membranes and predictive factors for major adverse outcomes.
- Author:
Hui-Min DONG
1
;
Juan SONG
1
;
Zhen-Zhen JUE
1
;
Le-Le WEI
1
;
Wen-Dong LI
1
;
Zhu-Ye ZHOU
1
Author Information
1. Department of Neonatology, Third Affiliated Hospital of Zhengzhou University/Henan Key Laboratory of Child Brain Injury/Henan Pediatric Clinical Research Center, Zhengzhou 450052, China.
- Publication Type:Journal Article
- MeSH:
Female;
Fetal Membranes, Premature Rupture;
Gestational Age;
Humans;
Infant;
Infant, Newborn;
Infant, Premature;
Infant, Premature, Diseases;
Infant, Very Low Birth Weight;
Pregnancy;
Retrospective Studies
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(6):575-581
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the clinical features of very preterm infants with prelabor rupture of membranes (PROM) and predictive factors for early-onset sepsis (EOS) and death.
METHODS:A retrospective analysis was performed for the clinical data of the very preterm infants with PROM (with a gestational age of < 32 weeks) who were admitted to the neonatal intensive care unit from January 2018 to May 2020. According to the time from membrane rupture to delivery, the infants were divided into four groups: < 18 hours (
RESULTS:There was no significant difference in the incidence rates of major neonatal complications and mortality rate among the very preterm infants with different times of PROM (
CONCLUSIONS:Prolonged PROM does not increase the incidence of neonatal complications and mortality in very preterm infants. Adverse outcomes of very preterm infants with PROM are mainly associated with lower birth weights, lung immaturity, and systemic infection.
