Association between the inter-aural latency difference of brainstem auditory evoked potential wave V and neonatal hyperbilirubinemia.
- Author:
Zong ZHENG
1
;
Hong-Yan LIU
1
;
Shan-Pu YANG
1
;
Li-Zhong DU
Author Information
1. Department of Pediatrics, People's Hospital of Yuhuan, Taizhou, Zhejiang 317600, China.
- Publication Type:Journal Article
- MeSH:
Bilirubin;
Evoked Potentials, Auditory, Brain Stem;
Hearing Loss;
Humans;
Hyperbilirubinemia;
Hyperbilirubinemia, Neonatal;
Infant, Newborn;
Prospective Studies
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(5):499-504
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study brainstem auditory evoked potential (BAEP) in neonates with hyperbilirubinemia using short auditory stimuli (60 dBnHL), and to investigate the differences in the inter-aural latency difference (ILD) of wave V between neonates with different total serum bilirubin (TSB) levels.
METHODS:A prospective study was conducted in neonates with hyperbilirubinemia who were admitted to the Department of Neonatology, Yuhuan People's Hospital of Zhejiang Province, from May 2019 to October 2020. The neonates were divided into a severe group (
RESULTS:Compared with the mild group, the severe group had significantly higher proportions of neonates with abnormal hearing threshold and abnormal ILD (
CONCLUSIONS:Serum bilirubin in neonates affects the ILD of BAEP wave V, especially in those with severe hyperbilirubinemia. ILD at the optimal cut-off value of ≥0.4 ms shows potential value in the diagnosis of hearing impairment caused by neonatal hyperbilirubinemia.
