Role and mechanism of histone deacetylases in mouse neuronal development.

Author: Yu-Wei BAI ¹ ; Meng-Long GUAN ¹ ; Tao ZHENG ¹ ; Shi-Ping LI ¹ ; Yi QU ¹ ; De-Zhi MU ¹
Author Information

1. Department of Pediatrics, West China Second University Hospital/Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University), Ministry of Education, Chengdu 610041, China.
Publication Type:Journal Article
MeSH: Animals; Blotting, Western; Histone Deacetylase 1/genetics*; Histone Deacetylase 2; Histone Deacetylases/genetics*; Immunohistochemistry; Mice; Neurons/metabolism*; Signal Transduction
From: Chinese Journal of Contemporary Pediatrics 2021;23(3):294-299
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To study the role and mechanism of histone deacetylase 1 (HDAC1) and histone deacetylase 2 (HDAC2) in mouse neuronal development.
METHODS:The mice with Synapsin1-Cre recombinase were bred with
RESULTS:The mice with
CONCLUSIONS:Deletion of