Association of different stages of histological chorioamnionitis with respiratory distress syndrome in preterm infants with a gestational age of < 32 weeks.
- Author:
Ran DING
1
;
Qiang CHEN
1
;
Qian-Wei ZHANG
1
;
Qi-Bin SUN
1
;
Dai-Jing WANG
1
;
Ruo-Bing SHAN
1
Author Information
1. Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shangdong 266000, China.
- Publication Type:Journal Article
- MeSH:
Birth Weight;
Child;
Chorioamnionitis/epidemiology*;
Female;
Gestational Age;
Humans;
Infant;
Infant, Newborn;
Infant, Premature;
Pregnancy;
Respiratory Distress Syndrome, Newborn/etiology*
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(3):248-253
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the association of different stages of histological chorioamnionitis (HCA) with the incidence rate and severity of respiratory distress syndrome (RDS) in preterm infants.
METHODS:Related data were collected from the infants and their mothers who were treated in the Neonatal Intensive Care Unit of Qingdao Women and Children's Hospital, Qingdao University, from January 2018 to June 2020. According to the presence or absence of HCA and its stage, the infants were divided into four groups: control (
RESULTS:Compared with the control and late-stage HCA groups, the early-stage HCA group had a significantly lower incidence rate of placental abruption and a significantly higher rate of prenatal use of antibiotics (
CONCLUSIONS:Early-, middle-, and late-stage HCA can reduce the incidence rate of RDS in preterm infants. HCA stage may not be correlated with RDS severity in preterm infants, which needs to be verified by further research.
