Clinical effect of multi-oil fat emulsion for parenteral nutrition support in extremely low birth weight infants.
- Author:
Hui-Jia LIN
1
;
Xiao-Xia SHEN
1
;
Ying-Hua NI
1
;
Xiao-Lu MA
1
;
Li-Ping SHI
1
;
Li-Zhong DU
1
Author Information
1. Department of Neonatal Intensive Care Unit, Children's Hospital, Zhejiang University School of Medicine/National Clinical Research Center for Child Health, Hangzhou 310052, China.
- Publication Type:Journal Article
- MeSH:
Birth Weight;
Emulsions;
Fat Emulsions, Intravenous;
Humans;
Infant;
Infant, Extremely Low Birth Weight;
Infant, Newborn;
Parenteral Nutrition;
Retrospective Studies;
Soybean Oil
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(3):229-235
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the clinical effect of multi-oil fat emulsion for parenteral nutrition support in extremely low birth weight (ELBW) infants.
METHODS:A retrospective analysis was performed for 49 ELBW infants who were admitted from January 1, 2018 to July 30, 2020, with an age of ≤14 days on admission and a duration of parenteral nutrition of > 14 days. According to the type of lipid emulsion received, the ELBW infants were divided into two groups: soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) (
RESULTS:The 49 ELBW infants had a mean birth weight of (892±83) g and a mean gestational age of (28.2±2.3) weeks. There was no significant difference between the two groups in the incidence rates of hemodynamically significant patent ductus arteriosus, intraventricular hemorrhage, neonatal necrotizing enterocolitis, retinopathy of prematurity, bronchopulmonary dysplasia (BPD), grade Ⅲ BPD, sepsis, and pneumonia (
CONCLUSIONS:The application of multi-oil fat emulsion in ELBW infants does not reduce the incidence rate of complications, but compared with MCT/LCT emulsion, SMOF can reduce the severity of PNAC in ELBW infants.
