Research advances in the treatment strategies for severe pertussis in children.
- Author:
Xiao-Ying WU
1
;
Li-Jun LI
;
Kai-Hu YAO
;
Hong-Mei XU
1
;
Zhou FU
Author Information
1. Department of Infection, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
- Publication Type:Review
- MeSH:
Anti-Bacterial Agents;
Child;
Exchange Transfusion, Whole Blood;
Humans;
Whooping Cough/drug therapy*
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(2):192-197
- CountryChina
- Language:Chinese
-
Abstract:
At present, effective antibiotics and comprehensive symptomatic/supportive treatment as early as possible are mainly used for the treatment of severe pertussis in clinical practice. However, some children with severe pertussis have unsatisfactory response to commonly used drugs and treatment measures in the intensive care unit and thus have a high risk of death. Studies have shown that certain treatment measures given in the early stage, such as exchange transfusion, may help reduce deaths, but there is still a lack of uniform implementation norms. How to determine the treatment regimen for severe pertussis and improve treatment ability remains a difficult issue in clinical practice. This article reviews the advances in the treatment of severe pertussis, in order to provide a reference for clinical treatment and research.
