Influence of premature rupture of membranes on the early prognosis of extremely premature infants.
- Author:
Su-E ZHANG
1
;
Xue-Yu CHEN
1
;
Chun CHEN
1
;
Xiao-Mei QIU
1
;
Bing-Chun LIN
1
;
Chuan-Zhong YANG
1
Author Information
1. Department of Neonatology, Affiliated Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University, Shenzhen, Guangdong 518028, China.
- Publication Type:Journal Article
- MeSH:
Chorioamnionitis;
Enterocolitis, Necrotizing/etiology*;
Female;
Fetal Membranes, Premature Rupture/epidemiology*;
Gestational Age;
Humans;
Infant;
Infant, Extremely Premature;
Infant, Newborn;
Pregnancy;
Prognosis
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(1):25-30
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the influence of premature rupture of membranes (PROM) on the early prognosis of extremely premature infants, and to provide a basis for the management of extremely premature infants and prenatal consultation.
METHODS:A total of 179 extremely premature singleton infants who were born from 2017 to 2019 were enrolled. According to the presence or absence of PROM, they were divided into two groups: PROM group (
RESULTS:Compared with the non-PROM group, the PROM group had significantly higher incidence rates of earlyonset sepsis and necrotizing enterocolitis (NEC) (
CONCLUSIONS:PROM increases the incidence rates of early-onset sepsis and NEC in extremely premature infants and does not increase the incidence rates of other adverse outcomes. For pregnant women with PROM at the risk of extremely preterm delivery, prevention of miscarriage and chorioamnionitis is recommended to prolong gestational weeks, reduce the incidence rate of infection, and thus improve the outcome of extremely premature infants.
