Association of fatty acid composition in human milk with breast milk jaundice in neonates.
- Author:
Li-Fei YANG
1
;
Jing LI
;
Rui HU
1
;
Li-Qing XU
1
;
Ya-Xuan LI
1
;
Wang-Tao SHENG
1
Author Information
1. Neonatal Intensive Care Unit, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.
- Publication Type:Journal Article
- MeSH:
Case-Control Studies;
Fatty Acids/analysis*;
Female;
Humans;
Infant, Newborn;
Jaundice, Neonatal/etiology*;
Milk, Human/chemistry*;
Nutrients/analysis*;
Pregnancy
- From:
Chinese Journal of Contemporary Pediatrics
2020;22(12):1256-1260
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the association of fatty acid composition in human milk with breast milk jaundice (BMJ) in neonates.
METHODS:A total of 30 full-term neonates who were admitted to the neonatal intensive care unit from October 2016 to October 2017 and were diagnosed with late-onset BMJ were enrolled as the BMJ group. Thirty healthy neonates without jaundice or pathological jaundice who were admitted to the confinement center during the same period of time were enrolled as the control group. Related clinical data were collected, including sex, mode of birth, feeding pattern, gestational age, birth weight, gravida, parity, and peak level of total serum bilirubin. Breast milk was collected from the mothers, and the MIRIS human milk analyzer was used to measure macronutrients (fat, protein, and carbohydrate) and calorie. Gas chromatography was used to analyze the content of different fatty acids in breast milk.
RESULTS:The control group had higher levels of macronutrients in human milk than the BMJ group, with significant differences in fat, dry matter, and calorie (
CONCLUSIONS:Some macronutrients and fatty acid composition in human milk may be associated with the pathogenesis of BMJ in neonates.
